Congratulations to Ali who successfully defended his PhD yesterday (6th July).

Dr Ali Sayqal’s PhD is on metabolomics for investigating drug and solvent stress on environmental bacteria. In particular Pseudomonas putida which included knockout in several important efflux pumps.

Read about his work here:

• Sayqal, A., Xu, Y., Trivedi, D.K., AlMasoud, N., Ellis, D.I., Rattray, N.J.W. & Goodacre, R. (2016) Metabolomics analysis reveals the participation of efflux pumps and ornithine in the response of Pseudomonas putida DOT-T1E cells to challenge with propranolol. PLoS ONE 11: e0156509.
• Sayqal, A., Xu, Y., Trivedi, D.K., AlMasoud, N., Ellis, D.I., Muhamadali, H., Rattray, N.J.W., Webb, C. & Goodacre, R. (2016) Metabolic analysis of the response of Pseudomonas putida DOT-T1E strains to toluene using Fourier transform infrared spectroscopy and gas chromatography mass spectrometry. Metabolomics 12: 112.
• Sayqal, A., Xu, Y., Trivedi, D., AlMasoud, N., Ellis, D.I. & Goodacre, R. (2016) Metabolic fingerprinting of Pseudomonas putida DOT-T1E strains: understanding the influence of divalent cations in adaptation mechanisms following exposure to toluene. Metabolites 6, 14.

Many thanks to Ali’s examiners Dr John Crosby (University of Bristol) and Prof Jon Lloyd.